BLASTphylo is an interactive web tool developed to compute and visualize taxonomic and phylogenetic trees of homologous proteins and genes. Including taxonomic or phylogenetic analyses into the process of characterizing a protein is common practice to gain insights into the protein’s evolutionary origin or to potentially deduce its function. The tool consists of an automated part that includes a BLAST search, a mapping of BLAST results onto the NCBI taxonomy, and phylogenetic tree computations. Both, taxonomic and phylogenetic trees are visualized interactively, allowing the user to (un)collapse nodes on demand. Additionally, the taxonomy can automatically be collapsed to different taxonomic ranks. By that, overview as well as detailed tree visualization can be created and downloaded.
Visit BLASTphylo here: https://blastphylo-tuevis.cs.uni-tuebingen.de/
Example Data
In order to get to know BLASTphylo we provide two demo datasets that can be loaded. For that, select ‘Demo’ as an input type and choose one of the two examples.
Data for the paper
Data used to generate figures from the paper can be found here: https://itnc.informatik.uni-tuebingen.de/index.php/s/qCawZesxWjG8J9f. The data is provided in a tabular BLAST output format and can be uploaded to BLASTphylo by selecting ‘BLAST result’ as the input type and by uploading the respective file.
Further links
GitHub: https://github.com/Integrative-Transcriptomics/BLASTphylo
BLASTphylo was presented at ISBRA 2022, Haifa, Israel.